The effect of synbiotics on ovarian function

The effect of synbiotics on ovarian function in women with poor ovarian response to ovulation stimulation in infertility treatment cycles: A randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251107067900N1

Enrollment

Registered

2025-12-19

Start date

2025-12-22

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poor ovarian response. Female infertility

Interventions

Intervention 1: Intervention group: Synbiotic administration (in the form of a sachet and daily) along with a pharmaceutical supplement for three months and then restarting the ovarian stimulation cy

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: poor response to gonadotropins in a previous IVF cycle AMH lower than 1.1

Exclusion criteria

Exclusion criteria: Thyroid dysfunction Congenital problems of the fallopian tubes Autoimmune diseases Hepatitis B and C and HIV positive Severe endometriosis Unwillingness to participate in the study

Design outcomes

Primary

Measure	Time frame
Ovarian volume and AFC measurement. Timepoint: After 3 month. Method of measurement: Transvaginal ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSareh Karimi

Mashhad University of Medical Sciences

Karimisareh@yahoo.com+98 51 3800 2466

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026