Cardiovascular complications and hemodynamic changes in patients under general anesthesia. Encounter for other preprocedural examination
Conditions
Interventions
Intervention 1: Intervention group: Propofol (2 mg/kg), intravenous emulsion, administered as an IV bolus for anesthesia induction immediately after pre-oxygenation and initial fluid administration. T
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: ASA1 & ASA2 patients Patients who are candidates for short elective surgeries (lasting less than two hours) under general anesthesia
Exclusion criteria
Exclusion criteria: History of general anesthesia within the past six months Pregnant women Patients with poorly controlled diabetes mellitus Patients with poorly controlled chronic obstructive pulmonary disease (COPD) Chronic use of analgesic or sedative medications Uncontrolled hypertension or cardiovascular disease, or prolonged use of beta-adrenergic blocking agents Predicted difficult airway management (Mallampati classification = III) History of hypersensitivity or allergic reaction to anesthetic agents used History of porphyria Body mass index (BMI) greater than 25 kg/m²
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Cardiac Monitoring.;Systolic Blood Pressure. Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Measured in millimeters of mercury (mmHg) using a calibrated sphygmomanometer.;Dyastolic Blood Pressure. Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Measured in millimeters of mercury (mmHg) using a calibrated sphygmomanometer.;Arterial oxygen saturation (SpO2). Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Pulse Oxymeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension. Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Calibrated sphygmomanometer.;Bradycardia. Timepoint: Before drug administration, at 1 and 3 minutes after induction of anesthesia, and at 1, 3, 5, and 10 minutes after intubation. Method of measurement: Cardiac monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDaryoosh Moradi Farsani
Esfahan University of Medical Sciences
Outcome results
None listed