Irreversible pulpitis in mandibular molars without periapical disease. Pulpitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 to 50 years. Mandibular molar tooth with irreversible pulpitis (confirmed by diagnostic tests such as cold test and percussion). Absence of systemic diseases No consumption of anti-inflammatory drugs in the 48 hours prior to treatment Ability to perform root canal treatment in a single session. Providing informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: Presence of symptoms such as abscess, fistula, or periapical radiolucency Consumption of any analgesic medication up to 8 hours prior to treatment. Consumption of alcohol or narcotic substances. Allergy to local anesthesia Pregnancy or breastfeeding. Significant medical history such as uncontrolled diabetes, renal failure, or active autoimmune diseases. Presence of another tooth with pulpal issues on the same side or opposite side. Teeth with root surface caries, root resorption, or calcified canals. Teeth that develop iatrogenic complications during treatment (such as perforation, instrument fracture, or inability to complete the treatment). Teeth with complex anatomy (such as taurodontism, severe curvature, or elongated roots). Teeth requiring multi-session treatment due to continuous exudate from the canal or hemorrhage. Patients with temporomandibular joint (TMJ) disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity. Timepoint: At before and 6, 24, 48, and 72 hours post-treatment. Method of measurement: Visual Analog Scale (VAS, 0-10). | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-treatment analgesic consumption. Timepoint: 6, 24, 48, and 72 hours after treatment. Method of measurement: Recording whether an analgesic was used or not at each time point, based on patient self-report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Birjand University of Medical Sciences