Postoperative sequelae following surgical extraction of impacted or semi-impacted mandibular third molars, specifically focusing on pain management and wound healing complications. The condition involves common postoperative symptoms including acute pain, inflammation, and delayed soft tissue recovery after mandibular third molar surgery. This study examines therapeutic interventions to improve recovery outcomes following this common oral surgical procedure.. Inflammatory conditions of jaws
Conditions
Interventions
Intervention 1: Intervention group: Oral Vitamin B-Complex tablets (2 tablets daily for one week) plus Ibuprofen as needed for pain management. Intervention 2: Control group: Identical placebo tablets
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Age: Between 18 and 35 years old. Health Status: Classified as ASA I (A normal healthy patient). Dental Condition: Required surgical removal of both left and right impacted or semi-impacted mandibular third molars (lower wisdom teeth).
Exclusion criteria
Exclusion criteria: Medication Use: Had used any non-steroidal anti-inflammatory drugs (NSAIDs) or analgesics in the one week prior to surgery. Substance Use: Were consumers of tobacco, alcohol, or illicit drugs. Pre-existing Infection: Had signs or symptoms of infection related to the third molar in the week before surgery. Allergy: Had a known allergy to compounds in the Vitamin B family. Systemic Diseases: Had any specific systemic diseases (this was asked in the patient information form to screen for ineligible conditions).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Pain Intensity: Measured using the Visual Analogue Scale (VAS), a 0-10 point scale where 0 represents "no pain" and 10 represents "the worst pain imaginable." Measurements are recorded at 1, 6, 12, 24, 48, and 72 hours after the surgical procedure. Wound Healing Status: Assessed clinically using a three-stage healing scale: 1) No healing (open wound with exposed bone), 2) Minimal healing with mucosal erythema, and 3) Healed with normal mucosa. Evaluations are performed at 2 weeks and 3 weeks post-surgery. Timepoint: Pain Intensity: Measured at 1, 6, 12, 24, 48, and 72 hours after the surgical intervention. Wound Healing Status: Assessed at 2 weeks and 3 weeks after the surgical intervention. Method of measurement: Pain Intensity: Measured using a standardized Visual Analogue Scale (VAS), a 10-cm horizontal line where the left end (0) represents "no pain" and the right end (10) represents "the worst pain imaginable." Patients self-report their pain level by marking a point on the line.Wound Healing Status: Assessed through direct clinical examination by a trained evaluator using a predefined three-stage healing scale based on visual inspection of the surgical site. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Ramadan
Islamic Azad University
Outcome results
None listed