Comparing the effects of different doses of Botox in the treatment of patients with resistant rhinitis to conventional treatment

Comparing the effects of different doses of botulinum toxin A (MASPORT 500) in the treatment of treatment resistant rhinitis

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251101067850N1

Enrollment

Registered

2025-12-11

Start date

2025-12-22

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment-resistant rhinitis. Vasomotor and allergic rhinitis

Interventions

Intervention 1: Second intervention group: In the head and trunk area of ??the middle and lower nasal turbinates of the patient, 50 units of botulinum toxin from the brand Mosport 500 will be injected

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: People with rhinitis who do not respond adequately to medical treatment or who suffer from side effects of medical treatments

Exclusion criteria

Exclusion criteria: Pregnancy Rhinosinusitis with or without polyposis Nasal anatomical abnormalities History of nasal and sinus surgeries History of immunotherapy History or presence of nasal and sinus malignancies

Design outcomes

Primary

Measure	Time frame
The amount of score reduction in the Total Nasal Symptom Score checklist. Timepoint: Before the injection, two weeks after, and then at six and twelve weeks after the injection. Method of measurement: Total Nasal Symptom Score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Azad

Bagheiat-allah University of Medical Sciences

dr.majidazad@yahoo.com+98 21 7711 8995

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026