Polycystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: Consumers of 500 mg licorice root capsules, one per day for 12 weeks. Intervention 2: Control group: Placebo capsule user, one capsule per day for 12 weeks.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women aged 18-45 Normal TSH levels Polycystic ovary syndrome (based on the Rotterdam criteria) Literate (able to read and write)
Exclusion criteria
Exclusion criteria: Smoking and alcohol addiction Receiving hirsutism treatments such as laser therapy (in the upper lip, chin, and lower abdominal areas) during the past three months. Use of any other hormonal medications during the past three months, based on self-report. Pregnancy and breastfeeding “Presence of other androgenic disorders such as congenital adrenal hyperplasia and androgen-secreting tumors.” Presence of systemic diseases such as cardiovascular, hepatic, renal and endocrine diseases, hypertension, neurosis and mental disorders hyperprolactinemia history of surgery for polycystic ovary syndrome, Allergy to licorice Occurrence of stressful events in the past three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Menstrual cycle. Timepoint: Entry into the study, after one month, after two months, after three months. Method of measurement: Menstrual pattern questionnaire.;Clinical hyperandrogenism. Timepoint: Entry into the study, after one month, after two months, after three months. Method of measurement: Freeman-Galway Scale and Global Acne Severity Scoring System (GAGS) questionnaire.;Biochemical hyperandrogenism. Timepoint: Entry into the study, after three months of intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Hadizadeh Talasaz
Mashhad University of Medical Sciences
Outcome results
None listed