Junctional Nevus. Melanocytic nevi, unspecified
Conditions
Interventions
Intervention 1: Intervention group 1: Patients with junctional nevus will receive combined treatment with Alexandrite laser and CO2 laser. The treatment will consist of 1 to 3 sessions with a 4-week i
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients having junctional nevus Patients who visited the hospitals belong to IAUMS Patients without chronic inflammatory state Patients without gestational state Patients without wound healing drugs consumption
Exclusion criteria
Exclusion criteria: Patients under 18 Immunosuppressive drugs consumption Pregnancy Patients with chronic inflammatory states Wound healing drugs consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of reduction in the size of the lesion. Timepoint: Before the intervention, after 6 months. Method of measurement: Visual Inspection; Palpation; Dermoscopy; Biopsy; Histopathology.;The rate of pain. Timepoint: During the intervention. Method of measurement: The visual analog scale (VAS).;The amount of reduction in the size of the nevus. Timepoint: Before the intervention, after 6 months. Method of measurement: Visual Inspection; Palpation; Dermoscopy; Biopsy; Histopathology. | — |
Secondary
| Measure | Time frame |
|---|---|
| Short-term complications (erythema, inflammation, blister). Timepoint: Immediately after each treatment session and up to 7 days following the intervention. Method of measurement: Clinical examination and documentation of complications by the treating physician; recorded in a standardized checklist.;Patient satisfaction level. Timepoint: One month and three months after the last treatment session. Method of measurement: Using a standardized patient satisfaction questionnaire (Likert scale from very dissatisfied to very satisfied).;Long-term complications (scar, hypo/hyperpigmentation). Timepoint: Three and six months after completion of treatment. Method of measurement: Clinical examination and photographic documentation compared with baseline images.;Number of treatment sessions. Timepoint: At the end of the treatment course. Method of measurement: Extracted from patient treatment records and session logs.;Recurrence rate within 6-month follow-up. Timepoint: Six months after the last treatment session. Method of measurement: Clinical examination and comparison with baseline clinical and photographic records.;Histopathological changes after treatment. Timepoint: Before treatment and after completion of treatment (if biopsy is clinically indicated). Method of measurement: Skin biopsy specimens (if clinically indicated) are examined using hematoxylin and eosin (H&E) staining under light microscopy by a dermatopathologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Yasemi
Islamic Azad University
Outcome results
None listed