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Evaluation of the Effect of Intraperitoneal Ketamine in Cesarean Section

Evaluation of the Effect of Intraperitoneal Ketamine on Pain and Postoperative Recovery Complications After Elective Cesarean Section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251029067816N1
Enrollment
60
Registered
2025-12-05
Start date
2025-12-22
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of the pain of pregnant women after cesarean section.

Interventions

Intervention 1: Intervention group: ? 0.5 mg/kg of ketamine diluted in 40 mL of normal saline will be instilled into the abdominal cavity before peritoneal closure. Intervention 2: Control group: 40 m

Sponsors

Karaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 49 Years

Inclusion criteria

Inclusion criteria: Pregnant women candidates for elective cesarean section for the second time? Gestational age term Maternal age 18–49 years? ASA II

Exclusion criteria

Exclusion criteria: ?Maternal underlying ?disease Emergency cesarean section ?Maternal age over 49 years or under 18 years ?History ?of allergy to ketamine ?Patients ?who used painkillers or sedative drugs 24 hours before surgery

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes and 6, 12 hours after cesarean section. Method of measurement: Visual analogue scale.;Blood pressure. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes after cesarean section. Method of measurement: Sphygmomanometer.;Pulse. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes after cesarean section. Method of measurement: Pulseoximeter.;Arterial oxygen saturation. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes after cesarean section. Method of measurement: Pulseoximeter.;Shivering. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes after cesarean section. Method of measurement: Clinical rating scale.;Nausea. Timepoint: 0, 15, 30, 45, 60, 75, 90, 105, 120 minutes after cesarean section. Method of measurement: Patient interview.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Alieh Rezaei

Karaj University of Medical Sciences

awliee.rezaei@gmail.com+98 26 3226 6851

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026