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Effect of topical Dexamethasone in the dental socket after surgery

Investigating the Effect of Topical Dexamethasone in Alveolar Socket on Pain and Complications After Impacted third molar Tooth Surgery: Clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251029067813N1
Enrollment
52
Registered
2025-11-07
Start date
2025-11-15
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The socket caused by impacted wisdom tooth surgery.

Interventions

Intervention 1: Intervention group: local anesthetic injection of inferior alveolar and long buccal nerve block with 2% lidocaine carpol containing epinephrine at 80000:1 will be performed, after whic

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 25 years With Impacted third Mandibular Molars Without Pericoronitis or Infection Who are not Pregnant Have no life-threatening Systemic Disease No Allergy to the Drugs used in the Study No recent use of Antibiotics or Anti-inflammatory Drugs Who are willing to participate in the Study

Exclusion criteria

Exclusion criteria: Those whose Follow-up for recording Pain and Swelling was not possible Who were unwilling to continue in the Study Individuals whose Healing process was not normal Patients who used other Anti-inflammatory Drugs or Antibiotics after Surgery Whose Impacted third Molars were located close to the Nerve Canal

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: The 2nd, 4th, and 7th Days After Surgery. Method of measurement: The Visual Analogue Scale will be used to measure the severity of patients' pain. The patient will be given a ten-centimeter ruler, numbered from 0 to 10, and the patient must indicate the level of pain on it on the second, fourth, and seventh days.

Secondary

MeasureTime frame
Facial swelling. Timepoint: The 2nd, 4th, and 7th days after surgery. Method of measurement: To measure swelling, we measure from the outer canthus of the eye to the mandibular protuberance, from the middle of the tragus of the ear to the outer corner of the lip on the same side in millimeter.;Trismus severity. Timepoint: The 2nd, 4th, and 7th days after surgery. Method of measurement: We measure the distance between the edges of the upper and lower incisors in millimeters.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Nadripour

Khoram-Abad University of Medical Sciences

Zahra.joudakii@gmail.com+98 916 363 1904

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026