Studying the effectiveness of zinc supplementation on reducing bilirubin in premature infants with hospitalized jaundice

Study of the effectiveness of zinc supplementation on reducing bilirubin 24, 48, and 72 hours after consumption in premature infants with jaundice hospitalized in Shahid Sadoughi Hospital, Yazd, in 1404.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251028067804N1

Enrollment

Registered

2025-11-04

Start date

2025-12-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal jaundice. Neonatal jaundice, unspecified

Interventions

Intervention 1: Intervention group: They will receive 1 cc per kilogram of the child's weight per day of zinc sulfate in a single dose as a syrup for three consecutive days. Intervention 2: Control gr

Eligibility

Sex/Gender

All

Age

1 Days to 10 Days

Inclusion criteria

Inclusion criteria: Physiological jaundice Weight 1500-2500 grams Gestational age between 30 and 37 weeks

Exclusion criteria

Exclusion criteria: Major congenital anomalies Severe respiratory failure History of blood transfusions History of IVIG Direct hyperbilirubinemia History of maternal phenobarbital use in the third trimester of pregnancy Parental lack of consent for study entry

Design outcomes

Primary

Measure	Time frame
Duration of phototherapy until bilirubin reaches below phototherapy level. Timepoint: After the intervention. Method of measurement: Calculation of days since the start of the intervention.;Mean serum bilirubin levels. Timepoint: Before intervention and 24, 48, 72 hours after intervention. Method of measurement: Blood test.;Hemoglobin mean. Timepoint: Before intervention and 24, 48, 72 hours after intervention. Method of measurement: Blood test.	—

Measure

Time frame

Duration of phototherapy until bilirubin reaches below phototherapy level. Timepoint: After the intervention. Method of measurement: Calculation of days since the start of the intervention.;Mean serum bilirubin levels. Timepoint: Before intervention and 24, 48, 72 hours after intervention. Method of measurement: Blood test.;Hemoglobin mean. Timepoint: Before intervention and 24, 48, 72 hours after intervention. Method of measurement: Blood test.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contactsamane rasouli sani abadi

Yazd University of Medical Sciences

samanerasouli3434@gmail.com+98 35 3822 3888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026