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The effectiveness of group therapy on opioid users undergoing treatment in Therapeutic Community

Comparative study of the effectiveness of Unified transdiagnostic group therapy (UP) and cognitive-behavioral group therapy (CBT) on reducing comorbid sleep problems, emotional disturbances, drug cravings and relapse prevention in Men with opioid use disorder living in Therapeutic Community (TC)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251027067788N1
Enrollment
45
Registered
2026-02-13
Start date
2025-12-06
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction. Opioid dependence, in remission

Interventions

Intervention 1: Intervention group: Unified transdiagnostic group therapy. This type of therapy identifies and targets factors that are common to multiple mental disorders. The 12-session protocol of
2011) will be used. This protocol consists of 12 60-minute sessions. Intervention 2: Intervention group 2: Cognitive-Behavioral Therapy (CBT) is a psychotherapy approach that uses a combination of cog

Sponsors

Tabassom Saeid par var
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Men with features of opioid use disorder in a Therapeutic Community Do not have a psychiatric disorder Have no history of specific medical disorders (such as head trauma, seizures, etc.) Literacy at least up to the first year of high school Recording the amount and type of sleeping medication used and being under treatment for at least three months in addiction treatment centers Willingness to participate in the study (informed consent) Treatment started within the last month Assessing substance use history and type(s) of substance used

Exclusion criteria

Exclusion criteria: Simultaneous use of multiple addictive substances Comorbidity with severe psychiatric disorders such as bipolar disorder, psychotic disorders, and other disorders that may overshadow the therapeutic relationship No motivation for treatment Mental retardation/disability Having a history of previous psychological interventions, especially CBT Diagnosis of a comorbid condition such as schizophrenia or bipolar disorder, or other conditions specifically other than impulsivity and sleep problems Changing the dosage of sleep medications

Design outcomes

Primary

MeasureTime frame
Comorbid sleep problems are the scores that subjects obtain on the Morin Insomnia Severity Index (ISI) (1993). Emotional disturbance is the score that the subject receives on the Depression, Anxiety, Stress Scale (DASS, Lavibond & Lavibond, cited in Anthony et al., 1998). Craving is the score that participants obtain on the Drug Craving Questionnaire (DDQ) developed by Franken et al. (2002). Relapse prevention is actually the result that the subject obtains on the Morphine Trial (TLC), such that a positive result indicates relapse and re-use, and a negative result indicates relapse prevention. Timepoint: The beginning of the study, the end of the study (about two months), and the two-month follow-up after treatment. Method of measurement: Drug Craving Questionnaire (DDQ). Morphine Test (TLC). Morin Insomnia Severity Index (ISI). Depression, Anxiety, Stress Scale (DASS). Unified Transdiagnostic Group Therapy (UP). Cognitive Behavioral Group Therapy (CBT). Psychiatric Symptom Checklist - Short Form (SCL-25). Structured Clinical Interview (SCID).

Countries

Iran (Islamic Republic of)

Contacts

Public Contacttabassom saeid par var

Iran University of Medical Sciences

intl@iums.ac.ir+98 21 8670 2030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026