Recurrent oral aphthea. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: Intervention group: 22 people receive mucoadhesive containing coriander extract. Intervention 2: Control group: Receive mucoadhesive without active ingredient (placebo).
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years of age without systemic disease who have had at least two recurrent episodes of aphthous stomatitis in the past year
Exclusion criteria
Exclusion criteria: Patients with autoimmune diseases Users of immunosuppressive drugs Pregnant women Traumatic wounds from sharp teeth, broken restorations, orthodontic appliances, or partial dentures Recurrent genital ulcers Eye and vision problems such as; eye pain, blurred vision, redness Recurrent infections; Unusual skin lesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound size: Measure the size of the wound. Timepoint: Days 0/3/7/10. Method of measurement: Duration of healing: Record the day the ulcer completely disappears. The recurrence rate is also measured one month later. Oral health impact questionnaire on daily life.;Pain intensity: Measured with a scale Healing time. Timepoint: Days 0/3/7/10. Method of measurement: Pain intensity measured by Visual Analogue Scale.The recurrence rate is also measured one month later. Oral health impact questionnaire on daily life. | — |
Secondary
| Measure | Time frame |
|---|---|
| The impact of oral health on quality of life. Timepoint: Days 1 and 10. Method of measurement: Questionnaire on the impact of oral health on daily life. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Mahjoub
Mashhad University of Medical Sciences
Outcome results
None listed