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?Radiofrequency ablation in thyroid nodules

Effectiveness of radiofrequency ablation therapy with ultrasound guidance in thyroid nodules

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251024067738N1
Enrollment
48
Registered
2025-11-04
Start date
2025-11-03
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign thyroid nodules - Autonomous thyroid nodule - Residual thyroid after thyroid cancer surgery - Residual metastatic lymph nodes after lymph node dissection for thyroid cancer.. Nontoxic single thyroid nodule

Interventions

Intervention group: Patients with benign nodules, autonomous thyroid nodules, thyroid remnants remaining after thyroid cancer surgery, and metastatic lymph nodes remaining after thyroid cancer lymph n

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with a definitive and documented diagnosis of autonomous nodule or benign thyroid nodule. Patients must be over 18 years of age. Patients with residual thyroid after thyroid cancer surgery. Patients with metastatic lymph nodes after lymph node dissection surgery for thyroid cancer. Patients with benign thyroid nodules less than 20 mm without clinical symptoms. Patients with a benign thyroid nodule greater than 20 mm with clinical symptoms. Patients with autonomous thyroid nodules less than 20 ml.

Exclusion criteria

Exclusion criteria: Patients who do not consent to participate in the research. Patients with known cases of dementia or psychiatric cognitive disorders. Patients under 18 years of age. Patients in whom the diagnosis of autonomous nodule or benign thyroid nodule is not definitive and documented. Patients with autonomous nodules with a volume greater than 20 ml.

Design outcomes

Primary

MeasureTime frame
Thyroid nodule volume reduction rate: It is created by dividing the difference between the pre- and post-thyroid nodule volume by the pre-thyroid nodule volume multiplied by 100. Timepoint: The volume of the thyroid nodule or lymph node is examined first and 3 and 6 months after the procedure. Method of measurement: The size of the thyroid nodule or lymph node is determined by ultrasonography of the thyroid or neck.

Secondary

MeasureTime frame
Minor and major complications resulting from ultrasound-guided radio frequency ablation procedure. Timepoint: Beginning of study, 3 and 6 months after the procedure. Method of measurement: History, physical examination, thyroid and neck ultrasound, and thyroid function test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdulhasan Talaeizadeh

Ahvaz University of Medical Sciences

Ahtalaiezadeh@yahoo.com+98 61 9101 0801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026