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Comparison of the effect of injectable lidocaine and lidocaine spray on hemodynamic responses

Comparison of the hemodynamic responses of intravenous lidocaine and lidocaine spray in the larynx area after laryngeal mask airway (LMA) placement in patients undergoing upper extremity orthopedic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251024067737N1
Enrollment
52
Registered
2025-10-30
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes associated with LMA insertion. Encounter for other preprocedural examination

Interventions

Intervention 1: Intervention group: Patients aged 18 to 50 years who are classified as ASA I or ASA II will be divided into two groups. In both groups, anesthesia will be induced with similar medicati

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients volunteering for upper limb orthopedic procedures Age between 18 and 50 years Physical status ASA Class I or II according to the American Society of Anesthesiologists

Exclusion criteria

Exclusion criteria: History of cardiovascular disease, uncontrolled blood pressure, or known arrhythmia Chronic respiratory disease or anticipated difficulty in intubation Hypersensitivity or allergy to lidocaine or other local anesthetics Pregnancy or lactation Use of medications affecting hemodynamic responses (such as beta-blockers or tricyclic antidepressants) Hepatic or renal failure

Design outcomes

Primary

MeasureTime frame
Blood pressure changes in response to different routes of lidocaine administration. Timepoint: Before the intervention and at 1, 3, 5, and 10 minutes after LMA insertion. Method of measurement: Monitoring device (operating room monitor).;Heart rate changes in response to different routes of lidocaine administration. Timepoint: Before the intervention and at 1, 3, 5, and 10 minutes after LMA insertion. Method of measurement: Monitoring device (operating room monitor).;O2 saturation(SPO2) changes in response to different routes of lidocaine administration. Timepoint: Before the intervention and at 1, 3, 5, and 10 minutes after LMA insertion. Method of measurement: Monitoring device (operating room monitor).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeedeh Besharatifar

Bandare-abbas University of Medical Sciences

saeedeh.besharatifar@gmail.com+98 76 3334 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026