Anemia in patients undergoing hemodialysis. Iron deficiency anemia
Conditions
Interventions
Intervention 1: Intervention group: For up to 90 days, patients will receive one gram of L-carnitine supplementation (2 capsules of 500 mg) per day. Intervention 2: Control group: For up to 90 days, p
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 20 and above Transferrin saturation percentage of at least 20% and ferritin level above 100 at the start of the study Hemoglobin level less than 11 Patients who have been on hemodialysis for more than 6 months No change in erythropoietin dose in the six months prior to the start of the study and during the study
Exclusion criteria
Exclusion criteria: Blood transfusion during the study Ongoing changes in hemodialysis rates during the study Erythropoietin dose changes during the study Occurrence of prolonged infection (more than one week) or inflammatory disease and malignancy during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood hemoglobin level. Timepoint: Study start, 45 days after treatment start and 90 days after treatment start. Method of measurement: Measuring blood hemoglobin levels. | — |
Secondary
| Measure | Time frame |
|---|---|
| Iron profile (Fe, TIBC, Ferritin) and MCV. Timepoint: Study start, 45 days after treatment start and 90 days after treatment start. Method of measurement: Measurement with blood test.;Lipid profile (TG, Chol, LDL, HDL). Timepoint: Study start, 45 days after treatment start and 90 days after treatment start. Method of measurement: Measurement with blood test.;Insomnia using the ISI questionnaire (Insomnia Severity Index). Timepoint: Study start, 45 days after treatment start and 90 days after treatment start. Method of measurement: Measurement with blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNarges Mostafalou
Babol University of Medical Sciences
Outcome results
None listed