Skip to content

A Comparative Study of the Effects of Citalopram 10 mg and Progressive Muscle Relaxation on Preventing Depression, Anxiety, Stress, Health Anxiety, and Obsessive–Compulsive Symptoms in Patients Following Ischemic Stroke

A Comparative Study of the Effects of Citalopram 10 mg and Progressive Muscle Relaxation on Preventing Depression, Anxiety, Stress, Health Anxiety, and Obsessive–Compulsive Symptoms in Hospitalized Patients Following Ischemic Stroke

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251022067726N2
Enrollment
180
Registered
2025-12-11
Start date
2025-12-16
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke. Cerebral infarction

Interventions

Intervention 1: Intervention group: During the 5 days of hospitalization in the neurology ward, patients in the citalopram intervention group will receive one tablet of citalopram 10 mg once daily dur

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?All patients diagnosed with ischemic stroke who admitted to the Neurology Departments .

Exclusion criteria

Exclusion criteria: First-ever ischemic stroke Age between 20 and 80 years NIHSS score < 12 DASS-21 scores: Depression = 6, Anxiety = 5, Stress = 9 Ability to read and write No history of central nervous system disorders such as dementia, Parkinson’s disease, or pre-stroke seizures No history of psychiatric disorders Absence of a history of drug or alcohol abuse or dependence Accessibility throughout the study period No chronic diseases such as cancer or chronic kidney failure

Design outcomes

Primary

MeasureTime frame
Depression score in the Depression, Anxiety, and Stress Scale questionnaire. Timepoint: Depression scores were measured at baseline and 33 days after the start of the study. Method of measurement: Depression subscale in the Depression, Anxiety, and Stress Scale questionnaire.;Anxiety score in the Depression, Anxiety, and Stress Scale questionnaire. Timepoint: Anxiety scores were measured at baseline and 33 days after the start of the study. Method of measurement: Anxiety subscale in the Depression, Anxiety, and Stress Scale questionnaire.;Stress score in the Depression, Anxiety, and Stress Scale questionnaire. Timepoint: Stress scores were measured at baseline and 33 days after the start of the study. Method of measurement: Stress subscale in the Depression, Anxiety, and Stress Scale questionnaire.;Health anxiety score in the Short Health Anxiety Inventory questionnaire. Timepoint: Health anxiety scores were measured at baseline and 33 days after the start of the study. Method of measurement: Short Health Anxiety Inventory questionnaire.;Obsessive–Compulsive score in the Yale–Brown Obsessive–Compulsive Scale questionnaire. Timepoint: Obsessive–Compulsive scores were measured at baseline and 33 days after the start of the study. Method of measurement: Yale–Brown Obsessive–Compulsive Scale questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Rezvaniamin

Zahedan University of Medical Sciences

mehdi.rezvaniamin@gmail.com+98 54 3341 9085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026