Condition 1: Strabismus. Condition 2: Strabismus. Other strabismus Paralytic strabismus
Conditions
Interventions
Intervention 1: The intervention group: recipients of intranasal dexmedetomidine at a dose of 1 microgram per kilogram, sprayed into both nostrils using a needleless syringe, approximately 45 minutes
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age above 18 years old Candidates for strabismus surgery under general anesthesia ASA physical score class I or II Standard preoperative fasting: at least 4 hours for clear fluids and 6 hours for solid food Written informed consent obtained from the participant (or their legal guardian, if applicable)
Exclusion criteria
Exclusion criteria: Pregnancy or lactation Use of antiemetic drugs (such as metoclopramide, ondansetron, or granisetron) Use of steroidal, opioid, or other emetogenic agents Presence of chronic diseases such as uncontrolled cardiac, renal, or diabetic disorders History of active vomiting within the past 24 hours Known hypersensitivity to the study drugs Psychiatric disorders or history of substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain score. Timepoint: 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Visual Analogue Scale score.;Patient satisfaction. Timepoint: 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Visual Analogue Scale score.;Need for rescue analgesia. Timepoint: 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Visual Analogue Scale score more than 4.;Postoperative Nausea and Vomiting. Timepoint: 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Yes or no.;Emergence Agitation. Timepoint: 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Yes or no.;Systolic, diastolic and mean arterial blood pressure. Timepoint: During surgery, 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Automatic blood pressure monitor.;O2 saturation. Timepoint: During surgery, 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Pulse Oximeter.;Pulse rate. Timepoint: During surgery, 30 minutes, 1 hour, 2 hours, 4 hours and 6 hours after surgery. Method of measurement: Pulse oximeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-anesthesia care unit stay duration. Timepoint: Every 1 hour. Method of measurement: Based on entrance and discharge time. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Azadian
Esfahan University of Medical Sciences
Outcome results
None listed