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Evaluation of the effect of tramadol on pain, nausea, and vomiting in patients with maxillofacial fractures

Evaluation of the effect of local tramadol injection on post operative pain, nausea, and vomiting in patients with maxillofacial fractures

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251014067623N1
Enrollment
56
Registered
2026-05-14
Start date
2026-06-22
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Oropharyngeal pain after simultaneous bilateral jaw surgery. Condition 2: Fracture of the lower jaw bone. Pain in throat Fracture of mandible

Interventions

Intervention 1: Intervention group: Morphine is administered at a dose of 0.1 mg/kg for intraoperative analgesia. After that, 10 minutes before the start of surgery (before incision) and before local

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with cheek fractures Patients with mandibular fractures

Exclusion criteria

Exclusion criteria: Patients with any history of neurological disease or disorder Patients with systemic diseases such as bleeding and coagulation disorders Pregnant women Patients with any history of drug use Patients with cardiovascular diseases and high blood pressure Patients with uncontrolled diabetes mellitus Patients with history of psychiatric diseases Breastfeeding

Design outcomes

Primary

MeasureTime frame
Pain in the upper or lower jaw area. Timepoint: At 30 minutes and 1 hour after entering recovery and 3, 6, and 12 hours after surgery. Method of measurement: Visual analog scale.;Nausea and vomiting. Timepoint: At 30 minutes and 1 hour after entering recovery and 3, 6, and 12 hours after surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohamadreza Moravej

Yazd University of Medical Sciences

Mohammad.moravvej451@gmail.com+98 35 3626 0001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026