The effect of curcumin supplementation on antibody levels and inflammatory markers in dialysis patients.

The impact of curcumin supplementation on serum levels of immunoglobulins and beta-2 microglobulin in hemodialysis patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251014067619N1

Enrollment

Registered

2025-11-04

Start date

2025-12-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney diseases.

Interventions

Intervention 1: Intervention group: Curcumin supplement 50 mg from Dineh, administered every 8 hours for 12 weeks. Intervention 2: Control group: Placebo

gelatin capsule containing maltodextrin, administered every 8 hours for 12 weeks.

Eligibility

Sex/Gender

All

Age

25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Dialysis history of 6 months or more

Exclusion criteria

Exclusion criteria: BMI over 30 History of malignancy Use of corticosteroids and other immunosuppressive drugs Use of NSAIDs

Design outcomes

Primary

Measure	Time frame
Serum levels of total IgG, IgM, and IgA. Timepoint: After 12 weeks of supplement consumption. Method of measurement: Nephelometry assay.;Serum levels of beta-2 microglobulin. Timepoint: After 12 weeks of supplement consumption. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Mardomi

Tabriz University of Medical Sciences

mardomia@tbzmed.ac.ir+98 41 3336 4665

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026