Studying the effect of vascular stromal component of adipose tissue obtained by mechanical method on treatment-resistant melasma

Investigating the effect of mechanical stromal vascular fraction (SVF) on refractory melasma

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251014067617N1

Enrollment

Registered

2025-11-12

Start date

2025-11-21

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatmet_resistant Melasma. Other melanin hyperpigmentation

Interventions

Intervention 1: Intervention group: In the intervention group, the procedure is as follows: under local anesthesia, 50 cc of fat is harvested from the abdomen, thigh, flank, or medial knee using a man

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Having treatment-resistant melasma Without using any other treatment method Being free of autoimmune disease

Exclusion criteria

Exclusion criteria: Having an autoimmune disease Having unrealistic expectations Simultaneous use of other treatment methods

Design outcomes

Primary

Measure	Time frame
Evaluation of Wood's lamp changes before and after treatment. Timepoint: Baseline, first month, third month, and sixth month. Method of measurement: Camera and Wood's lamp images.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadi Sidi Rad

Mashhad University of Medical Sciences

Hadiseidirad1987@gmail.com0513854303

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026