Patients with diabetes treated with pills. Acute kidney failure, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Dexmedetomidine (Medonex) diluted in saline at a concentration of 0.5 micrograms/kg/hour) In the placebo group, normal saline solution was administered via an infus
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: EF>35% Diabetic patient treated with medication Candidate for Elective CABG On-Pump beating with two or more grafts, provided that one of the grafts is the left internal mammary artery (LIMA) HR > 65 on arrival GFR>50 ASA Class II classification Hct>30% The patient shouldn't have emergency surgery, concurrent valve surgery, or underlying renal, pulmonary, gastrointestinal, hepatic, or thyroid disease. Age between 35 to 70
Exclusion criteria
Exclusion criteria: Reoperations and non-coronary procedures CABG Off-Pump Return to the operating room from the ICU History of previous heart surgery History of fever, trauma Bilateral carotid artery stenosis > 50% Intubation difficult or takes longer than 20 seconds BMI > 30 kg/m² HR>65 LM>50% History of bundle branch block History of treatment with clonidine or methyldopa IABP
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative AKI in diabetic patients undergoing CABG who received dexmedetomidine. Timepoint: The incidence of AKI is determined by measuring urea and creatinine before, during, and after surgery. Method of measurement: Blood test and urine output. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDR.Mahdi Kahrom
Mashhad University of Medical Sciences
Outcome results
None listed