effect of intraoperative dexmedetomidine on the improvement of gastrointestinal function after abdominal surgery

Investigating the effect of intraoperative dexmedetomidine on the improvement of gastrointestinal function after abdominal surgery: a clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251011067593N1

Enrollment

188

Registered

2025-10-20

Start date

2025-10-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive system function.

Interventions

Intervention 1: Intervention group: Dexmedetomidine with an initial dose of 0.5 µg/kg over 15 minutes, then a maintenance dose of 0.2 µg/kg/h until 30 minutes before the end of the procedure. Interven

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Elective abdominal surgery candidates Age between 18 and 65 years ASA physical status class I or II Providing written informed consent to participate in the study No history of substance abuse, alcohol consumption, smoking, or use of psychoactive drugs

Exclusion criteria

Exclusion criteria: Decreased level of consciousness Hemodynamic instability during surgery Excessive intraoperative bleeding Duration of surgery exceeding 4 hours

Design outcomes

Primary

Measure	Time frame
Time of first gas release. Timepoint: After the intervention. Method of measurement: Based on time of first occurrence.	—

Secondary

Measure	Time frame
Length of hospital stay. Timepoint: After the intervention. Method of measurement: Based on the number of days.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mobin Alishahi

Tehran Azad University of Medical Sciences

mobinalishahi80@gmail.com+98 21 3350 5372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026