A comparative study on the effect of combined pelvic floor physiotherapy versus duloxetine for the control of urinary symptoms following prostate surgery

A Comparative Study on the Effect of Combination Therapy with Biofeedback and PTNS versus Duloxetine for the Control of Urinary Symptoms Caused by Radical Prostatectomy in Patients Referred to the Rehabilitation Clinic of Imam Khomeini Hospital, 2025–2026

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251009067565N1

Enrollment

Registered

2026-04-24

Start date

2026-04-30

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary incontinence. Other specified urinary incontinence

Interventions

Intervention 1: Intervention group: Biofeedback + PTNS. Intervention 2: Control group: Duloxetine 20 mg once daily.

Eligibility

Sex/Gender

Male

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: At least 3 weeks have passed since the prostatectomy Presence of at least one urinary symptom (frequency, urge urinary incontinence, or stress urinary incontinence) with a specified score on the standard IPSS questionnaire No use of medications affecting bladder function in the past 4 weeks

Exclusion criteria

Exclusion criteria: History of neurogenic bladder disorders Active urinary tract infection Unwillingness to continue participation in the study Non-attendance for Biofeedback and PTNS for 2 consecutive sessions

Design outcomes

Primary

Measure	Time frame
Change in IPSS score. Timepoint: Before treatment and 3 months after treatment completion. Method of measurement: Standard IPSS questionnaire (7 items).;Number of urinary incontinence episodes in 24 hours. Timepoint: Before treatment and 3 months after treatment completion. Method of measurement: Patient questioning and recording of frequency.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Alavi Eshkaftaki

Tehran University of Medical Sciences

fatemealavi624@gmail.com0098 21 61190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026