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The comparison of oral ketorolak and diclofenac in bilateral lower wisdom teeth

The comparison of the effects of two oral drugs of diclofenac and ketorolac in pain, swelling and trismus control of patients under bilateral surgery of mandibular impacted third molar teeth.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251008067557N1
Enrollment
36
Registered
2025-10-27
Start date
2025-10-06
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral impaction of lower wisdom teeth.

Interventions

Intervention group: Candidates for bilateral lower wisdom teeth surgery.

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: The patient must be young (under 20 years old and over 35 years old), or otherwise (over 35 years old) must be symptomatic ( meaning they have symptoms such as pain, swelling, inflammation, infection, trismus, etc.) and must not have any uncontrolled systematic disease that would interfere with the surgery and must have impacted or semi-impacted wisdom teeth in the lower jaw on both sides and with the same depth and angle and must have the needed consent and cooperation to perform this surgery, participate in this research project, and refer to follow-up meetings.

Exclusion criteria

Exclusion criteria: The patient is over 35 years old and has no signs or symptoms, or has an uncontrolled systematic condition that interferes with the surgery or impaction, or semi-impaction of the patient is not bilateral, or does not have the same depth and angle, or does not have the needed consent and cooperation to perform this surgery and participate in this research project, or has a contraindication to NSAID use.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 6,48 hours and one week after surgery. Method of measurement: the patients pain severity will be measured according to the patients opinion via VAS (visual analogue scale) at specified intervals and the patient will rate their pain severity feom 0 to 10.;Swelling. Timepoint: 6,48 hours and one week after surgery. Method of measurement: The Laskin method will be used for measuring the patients swelling. this measurement is taken once before surgery and then after surgery at the specified intervals and the difference in these values after and before the surgery will show us the severity of patients swelling .;Trismus. Timepoint: 6,48 hours and one week after surgery. Method of measurement: the severity of patients trismus will be measured according to the maximum opening of mouth scale. this scale will be once measured before the surgery and then after the surgery in the specified intervals and the amount of decreasing in this scale will show us the severity of the patients trismus.

Countries

Iran (Islamic Republic of)

Contacts

Public Contacterfan afxamy

Tabriz University of Medical Sciences

erfanafxamy78@gmail.com+98 41 3334 9022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026