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Evaluation of the effectiveness of Milrinone in the treatment of patients with aluminum phosphide poisoning .

Evaluation of the effectiveness of Milrinone in the treatment of patients with aluminum phosphide poisoning.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251008067554N1
Enrollment
46
Registered
2025-11-15
Start date
2022-09-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aluminum Phosphide Poisoning. -

Interventions

Intervention 1: Intervention group: Treated with milrinone in addition to conventional treatments for aluminum phosphide poisoning (according to the Ministry of Health protocol). Intervention 2: Contr

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients had a documented history of aluminum phosphide consumption. Onset of symptoms of cardiogenic shock within the first 6 hours of hospitalization

Exclusion criteria

Exclusion criteria: Absence of any clinical or paraclinical signs or symptoms of aluminum phosphide poisoning within the first 6 hours of hospital admission Sensitivity to the drugs being studied

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: Every hour after admission to the hospital until 48 hours after the start of treatment. Method of measurement: Patients' systolic blood pressure is automatically monitored by a vital signs monitor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Poorrajabi Firoozabad

Tehran University of Medical Sciences

hpourrajabi1982@gmail.com+98 35 3234 5508

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026