The effect of combined massage therapy and music therapy on symptom clusters including pain, fatigue, and sleep disturbance in patients with advanced cancer

The effect of combined massage therapy and music therapy on symptom clusters including pain, fatigue, and sleep disturbance in patients with advanced cancer undergoing chemotherapy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251008067551N1

Enrollment

Registered

2025-11-02

Start date

2025-11-10

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer. Multiple myeloma and malignant plasma cell neoplasms

Interventions

Intervention 1: Intervention group 1:Massage therapy group: 30-minute massage sessions 3 times a week for 4 weeks. Intervention 2: Intervention group 2: 30-minute music therapy sessions, 3 times a wee

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Advanced cancer (stage 3 or 4 according to the TNM system) (Advanced cancer is a stage of the disease in which the cancer can no longer be definitively cured, but it can still be controlled or slowed down with various interventions.) Outpatients aged between 18 and 64 years Experience pain intensity, fatigue, and sleep disturbance of 4 or more in the past 24 hours (on a numerical rating scale of 0 to 10) prior to the intervention. Absence of a clear and recognized pain, fatigue, or sleep disorder mentioned in the patient's medical history that is not caused by cancer. Do not have underlying diseases such as diabetes, peripheral neuropathy, skin diseases in the massage area, and addiction. Treatment should not be performed in the area of ??the cancerous tumor. Do not have rheumatoid arthritis, spinal cord injury, or bone disease that can be made worse by physical manipulation. Do not have varicose veins The patient's platelet level is above 15,000 per cubic millimeter. Do not have a hearing problem that prevents you from listening to music.

Exclusion criteria

Exclusion criteria: Failure to attend three consecutive or four scattered intervention sessions Patient's unwillingness to continue participating in the study The occurrence of acute problems during the study (problems such as hospitalization, surgery, etc.) death of the patient

Design outcomes

Primary

Measure	Time frame
Pain, fatigue, sleep disturbance based on numerical rating scale (NRS). Timepoint: (before the intervention) and 7, 14, 21 and 28 days after performing music and massage therapy. Method of measurement: numerical rating scale (NRS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Sayadi

Ahvaz University of Medical Sciences

sayadi-n@ajums.ac.ir+98 61 3373 8331

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026