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Evaluation of the effect of clonazepam in pain control after photorefractive keratectomy surgery

Comparative study of the effectiveness of clonazepam in controlling postoperative pain in patients undergoing photorefractive keratectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251008067549N1
Enrollment
200
Registered
2025-10-30
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia, Hyperopia, Astigmatism, Photorefractive keratectomy.

Interventions

Intervention 1: Intervention group: In addition to the nonsteroidal anti-inflammatory drug Novafen, 1 tablet every 8 hours for 3 days after surgery from Razek Pharmaceutical Company, they will receive

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age over 18 years and under 65 years Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having a history of mental illness Presence of stomach ulcers and pud Addiction Unwillingness to participate in the study History of diabetes Corticosteroid use within the last month History of benzodiazepine and tricyclic drug use within the last two weeks Alcohol abuse History of obstructive sleep apnea Myasthenia gravis History of liver disease History of severe respiratory failure

Design outcomes

Primary

MeasureTime frame
Pain levels of patients after Photorefractive keratectomy surgery. Timepoint: Pain levels of patients after Photorefractive keratectomy surgery at 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Determining and comparing complications in the two intervention and control groups. Timepoint: Determination and comparison of complications in the intervention and control groups 12 and 24 hours after surgery. Method of measurement: Questions on the day after surgery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Khajavi Ghare Mirshamloo

Zahedan University of Medical Sciences

af.khajavi94@gmail.com+98 71 3642 3923

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026