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Evaluation of the Effect of Intravenous Methylprednisolone Injection on Sore Throat Caused by General Anesthesia

Evaluation of the Effect of Intravenous Methylprednisolone Injection on Sore Throat Caused by General Anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251007067539N1
Enrollment
100
Registered
2025-10-12
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat from general anesthesia.

Interventions

Intervention 1: Intervention group: In the intervention group, prior to induction of anesthesia, patients will receive Methylprednisolone succinate (manufactured by Jaber Ibn Hayyan Pharmaceutical Com

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patient provides informed consent to participate in the study The patient's age is between 18 and 65 years. The patient has no known hypersensitivity to methylprednisolone. The patient has no underlying medical conditions The patient does not have any immunodeficiency disorders.

Exclusion criteria

Exclusion criteria: Known drug hypersensitivity to methylprednisolone. Lack of patient cooperation during the study. History of chronic sore throat. Recent history of upper respiratory tract infection. History of osteoporosis. Multiple attempts at tracheal intubation.

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: The Visual Analogue Scale(VAS) pain score will be recorded in both groups upon admission to the recovery room, 6 hours after extubation, and 24 hours after extubation. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSadaf jalili

Zahedan University of Medical Sciences

sadafjalili111@gmail.com+98 992 841 5720

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026