The study focuses on sudden hemodynamic responses — increased blood pressure and heart rate — caused by skull-pin fixation during general anesthesia in posterior cervical spine fusion surgery..
Conditions
Interventions
Intervention 1: Intervention group: the intervention group will receive 1 microgram per kilogram of bodyweight of intranasal dexmedetomidine in each nostril 30 minutes before the induction of anesthes
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 65 years who are candidates for elective posterior cervical fusion surgery. ASA I ? II
Exclusion criteria
Exclusion criteria: Patient’s refusal or withdrawal from participation at the final stage Difficulty in intubation using a Glidescope, requiring more than one attempt or lasting more than 10 seconds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This randomized clinical trial investigates the effect of intranasal dexmedetomidine on hemodynamic responses during skull-pin fixation in posterior cervical spine surgery under general anesthesia. Timepoint: Hemodynamic variables will be measured at baseline, after intranasal drug administration, before and after skull-pin fixation, and every three minutes until surgical incision. Method of measurement: Blood pressure, heart rate, and oxygen saturation will be measured using standard operating room monitoring devices: non-invasive blood pressure (NIBP), electrocardiography (ECG), end-tidal CO2 (ETCO2), and pulse oximetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Baghaie Vaji
Esfahan University of Medical Sciences
Outcome results
None listed