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Effect of resistance training with and without transcranial direct current stimulation on upper limb recovery after stroke

Investigation the effectiveness of adding transcranial direct current stimulation to resistance exercise on function, quality of life, and movement smoothness of the upper limbs in individuals with stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20251006067516N1
Enrollment
24
Registered
2025-12-09
Start date
2025-12-21
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb of patients with stroke.

Interventions

Intervention 1: Intervention group: Intervention A-tDCS Initially, for 20 minutes, this protocol is applied to patients assigned to this group. Considering that previous studies have reported tDCS af

Sponsors

The University of modares
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Ischemic hemiplegia Stroke in the territory of the middle cerebral artery At least three months since the event Fugl-Meyer Assessment upper-extremity score between 18 and 48 Shoulder pain with a Visual Analog Scale (VAS) score less than 3 Modified Ashworth Scale score for the biceps muscle of 2 No cognitive or perceptual impairments that would hinder following the treatment process (MMSE score at least 18) Written informed consent form confirmed for participation in the study

Exclusion criteria

Exclusion criteria: Complex Regional Pain Syndrome Patients with depression who are unable to participate in treatment Cardiovascular problems Other problems in neurology, orthopedics, and rheumatology Presence of severe comorbidities Presence of contracture

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment. Timepoint: Before and after six weeks of treatment. Method of measurement: Thirty-three items pertain to the upper limb, including the shoulder, elbow, forearm, and wrist. The test is scored based on direct observation of performance, with each item scored from 0 to 2. If a person cannot perform the movement, the score is 0; if the movement is performed partially, the score is 1; if the movement is performed fully, the score is 2.;Modified Ashworth Scale: It is a ranked scale for measuring spasticity. Timepoint: Before and after six weeks of treatment. Method of measurement: t is rated on a scale from zero to four. Grade 2 indicates a clear increase in muscle tone that is evident when the joint is held in a specified range, but the limb(s) can be moved easily.;Maximum muscular power: For measuring the strength (in kilograms) of the muscles of the upper limb, including flexors, extensors, abductors, adductors, internal and external rotators of the shoulder, flexors and extensors of the elbow, using a nerve stimulator (Lafayette Company. Timepoint: Before and after six weeks of treatment. Method of measurement: Each test will be performed three times: once by the examiner for training, once by the patient to learn how to perform it, and once again by the patient to perform it. Muscle power measurements for two directions, flexion and abduction, will be carried out once in the lower position and once in the upper position using a nerve stimulator (Lafayette Company).;Maximum range of motion for shoulder flexion and abduction. Timepoint: Before and after six weeks of treatment. Method of measurement: For measuring the range of motion (ROM) of shoulder abduction, the patient sits on a chair and the examiner holds the fixed arm of the goniometer completely perpendicular to the trunk in the frontal plane, with the goniometer's axis centered on the acromion process. The movable arm of the goniometer follows the arm and runs along the lateral epicondyl

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Sadeghnia

The University of Modares

dpttehran@gmail.com+98 21 8288 2009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026