Studying the effect of fractional CO2 laser in the treatment of alopecia areata

Comparative study of the effectiveness of fractional CO2 laser with topical triamcinolone acetonide versus intralesional triamcinolone acetonide injection in the treatment of patients with alopecia areata

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20251003067487N1

Enrollment

Registered

2025-10-12

Start date

2025-10-12

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia Areata. Alopecia areata

Interventions

Intervention 1: Control group: Alopecia patches are mapped on a transparent sheet and a graph paper to calculate the area of ??each patch in square centimeters. In the control patch, intralesional inj

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with alopecia areata over 15 years of age Have at least 2 or more comparable, anatomically similar, symmetrical allopathic patches on both sides of the head at least 2 cm apart. Alopecia severity scoring system is less than 25%. They have not received systemic medication or intralesional injection effective for alopecia areata in the last 2 months.

Exclusion criteria

Exclusion criteria: Immunocompromised patients Pregnant patients Patients with systemic diseases - cardiac, renal and hepatic disorders

Design outcomes

Primary

Measure	Time frame
Severity of ALopecia Tool (SALT) Score. Timepoint: Before the intervention begins - at each session - one month after the end of treatment. Method of measurement: As observed by a dermatologist and scored according to the relevant system/Scoring is based on clinical and dermoscopy photographs.;Pain. Timepoint: After each treatment session. Method of measurement: Visual discomfort scale (VDS).;Patient satisfaction with hair growth. Timepoint: After each treatment session. Method of measurement: Visual analogue scale (VAS).	—

Measure

Time frame

Severity of ALopecia Tool (SALT) Score. Timepoint: Before the intervention begins - at each session - one month after the end of treatment. Method of measurement: As observed by a dermatologist and scored according to the relevant system/Scoring is based on clinical and dermoscopy photographs.;Pain. Timepoint: After each treatment session. Method of measurement: Visual discomfort scale (VDS).;Patient satisfaction with hair growth. Timepoint: After each treatment session. Method of measurement: Visual analogue scale (VAS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges ghandi

Tehran University of Medical Sciences

Nghandi@tums.ac.ir+98 21 5561 8989

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026