Chronic Periodontitis. Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group: Scaling and root planing with administration of folic acid tablets (1 mg - Raha Pharmaceutical Company – Iran) once daily for four weeks
tablets are taken during meals and consumption with milk or dairy products is avoided. Intervention 2: Control group: Scaling and root planing with administration of placebo tablets (containing an ina
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
31 Years to 61 Years
Inclusion criteria
Inclusion criteria: Patients aged 31 to 61 years at least 8 pockets with a depth of 5 mm or more a clinical attachment level (CAL) of =4 mm stage II-III periodontitis (corresponding to "moderate to severe" in the previous classification).
Exclusion criteria
Exclusion criteria: Have systemic conditions including anemia, diabetes, immunodeficiency, malignancy, bone metabolic diseases/disorders, renal or thyroid dysfunction, radiotherapy, treatment with immunosuppressive agents, or gastrointestinal diseases. Patients who consume alcohol, smokers, obese individuals, or those who are pregnant or breastfeeding. have received periodontal treatment within the past year. have received anti-inflammatory or antimicrobial treatment, or iron/vitamin supplements within the past three months. lack of cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical attachment level. Timepoint: before treatment and at 1-month and 3-month periods after treatment . Method of measurement: William's periodontal probe. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque index. Timepoint: before treatment and at 1-month and 3-month periods after treatment. Method of measurement: The Plaque Index (PI) has 4 scores, each defined as follows: Score 0: No plaque Score 1: Plaque becomes visible after moving the probe along the gum line Score 2: Visible plaque Score 3: Abundant plaque.;Gingival index. Timepoint: before treatment and at 1-month and 3-month periods after treatment. Method of measurement: The Gingival Index (GI) has 4 scores, each defined as follows: Score 0: Absence of visible signs of gingival inflammation Score 1: Slight change in the color and surface texture of the gingiva Score 2: Visible inflammation and tendency for bleeding from the gingival margin immediately after probing Score 3: Severe inflammation and tendency for spontaneous bleeding.;Pocket depth. Timepoint: before treatment and at 1-month and 3-month periods after treatment . Method of measurement: William's periodontal probe ( millimeter).;Gingival recession. Timepoint: before treatment and at 1-month and 3-month periods after treatment. Method of measurement: William's periodontal probe ( millimeter).;C-Reactive Protein (CRP) serum level. Timepoint: before treatment and at 1-month and 3-month periods after treatment . Method of measurement: The level of C-reactive protein in the blood (mg/L), measured using a Biorex kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahar Azizi
Yazd University of Medical Sciences
Outcome results
None listed