pruritus of intrathecal Fentanyl in spinal anesthesia.
Conditions
Interventions
Intervention 1: Intervention group: Patients receiving one capsule pregabalin 100MG PO under the trade name LYRICER ,from Actoverco Pharmaceutical Company with a small amount of water one hour Abefore
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 years who are candidates for elective lower leg surgery under Spinal anesthesia Individuals with an American Society of Physical Therapists (ASA) grade I or II condition no history of pregabalin or fentanyl allergy no use of gabapentinoids in the last week
Exclusion criteria
Exclusion criteria: Contraindications for spinal anesthesia Refusal to continue studying Need to convert spinal anesthesia to general anesthesia Any complaints of skin itching before surgery Known history of hypersensitivity to pregabalin or severe adverse reactions to pregabalin (such as skin rash or angioedema) Current skin disease Any systemic disease accompanied by itching Patients receiving glucocorticoids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Itching severity. Timepoint: 1 , 2 , 6 , 12 , 24 hour after Spinal anesthesia. Method of measurement: Visual Analogue Scale.;Time of itching outbreak. Timepoint: 1 , 2 , 6 , 12 , 24 hour after Spinal anesthesia. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Before the intervention begins. Method of measurement: Kilogrammes.;Need for adjuvant treatment. Timepoint: 1,2,6,12,24 hour after Spinal anesthesia. Method of measurement: Need or not need.;Patient satisfaction with itching control. Timepoint: 1,2,6,12,24 hour after Spinal anesthesia. Method of measurement: Based on a Visual Analogue Scale from 0 to 10.;Side effects of medication. Timepoint: Up to 24 hours after the intervention. Method of measurement: Existence or non-existence. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mehrdad Malekshoar
Bandare-abbas University of Medical Sciences
Outcome results
None listed