fibrom. Leiomyoma of uterus, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Demographic characteristics of patients (age, weight, BMI, reason for referral) will be recorded. Then, initial hemoglobin level and initial serum vitamin D3 level
Sponsors
Qazvin University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1- Confirmation of the presence of at least one fibroid measuring 20-80 mm on abdominal or vaginal ultrasound by a radiologist Serum vitamin D level of 20-30 ng/ml
Exclusion criteria
Exclusion criteria: History of hormonal medication use uterine fibroid treatment in the past 3 months history of vitamin D supplementation in the past 6 months severe vaginal bleeding adenomyosis evidence of malignancy menopause metabolic diseases lack of follow-up visits sensitivity to vitamin D desire to become pregnant inability to follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibroid size. Timepoint: Before the start of the intervention and after 4 and 8 weeks from the start of the intervention. Method of measurement: Ultrasound and testing.;Number of fibroids. Timepoint: Before the start of the intervention and after 12 months from the start of the intervention. Method of measurement: Ultrasound.;Hemoglobin level. Timepoint: Beginning of the intervention and end of the intervention. Method of measurement: Test.;Vitamin D3 levels. Timepoint: Beginning of the intervention and end of the intervention. Method of measurement: test.;Age. Timepoint: Beginning of the intervention. Method of measurement: Hospital Information System.;Pelvic pain (dysmenorrhea, menorrhagia). Timepoint: Beginning of the intervention and end of the intervention. Method of measurement: Clinical examination.;Urinary symptoms. Timepoint: Beginning of the intervention and end of the intervention. Method of measurement: Clinical examination.;BMI. Timepoint: Beginning of the intervention. Method of measurement: Scales and meters.;Location of fibroids. Timepoint: Beginning of the intervention and end of the intervention. Method of measurement: Ultrasound.;Age of onset of menarche. Timepoint: Beginning of the intervention. Method of measurement: Question.;Side effects of vitamin D. Timepoint: Start of intervention, 4 and 8 weeks after intervention, and at the end of the study. Method of measurement: Clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fibroid size. Timepoint: First and last reading. Method of measurement: Ultrasound.;Number of fibroids. Timepoint: First and last reading. Method of measurement: Ultrasound.;Hemoglobin level. Timepoint: First and last reading. Method of measurement: test.;Vitamin D3 levels. Timepoint: First and last reading. Method of measurement: TEST. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactfatemeh moghadam
Qazvin University of Medical Sciences
Outcome results
None listed