Comparative efficacy of electrocautery as monotherapy and in combination with immunotherapy in treatment of perianal warts

Comparative efficacy of electrocautery as monotherapy and in combination with immunotherapy in treatment of perianal warts, a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250930067437N1

Enrollment

Registered

2025-10-06

Start date

2025-10-11

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perianal warts. Anogenital (venereal) warts

Interventions

Intervention 1: In the intervention group, treatment will be conducted as follows: After the diagnosis of perianal warts by a colorectal surgeon, the lesions will first be treated with Imiquimod 5% cr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with perianal lesions caused by HPV Willingness to participate in the study (informed consent)

Exclusion criteria

Exclusion criteria: Corticosteroid use Coagulation disorders Pregnancy Presence of a cardiac pacemaker

Design outcomes

Primary

Measure	Time frame
The rate of complete lesion clearance at the end of the treatment period. Timepoint: 2, 4 and 6 months after the intervention. Method of measurement: Data Collection Form.	—

Secondary

Measure	Time frame
The incidence of treatment-related adverse events. Timepoint: 2, 4 and 6 months after the intervention. Method of measurement: Data Collection Form.;The recurrence rate of lesions. Timepoint: Six months after the intervention. Method of measurement: Data Collection Form.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Noroozian Reikandeh

Mazandaran University of Medical Sciences

r.norouzian@mazums.ac.ir+98 11 3335 6329

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026