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The effect of ozone gel on tooth extraction pain

Evaluation of Topical Application of Ozone Gel on Pain and Dry Socket Incidence After Molar Tooth Extraction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250930067435N1
Enrollment
34
Registered
2025-10-03
Start date
2025-10-04
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after molar tooth extraction. Open wound of lip and oral cavity

Interventions

Intervention 1: Intervention group: 1 cc of ozone gel (made by ATRIN brand in Iran or a similar product) is placed on the gauze and the patient packs it for 30 minutes, and no antibiotics will be pres

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who are candidates for extraction of non-retainable molars

Exclusion criteria

Exclusion criteria: Patients with vascular or blood disorders Users of exogenous corticosteroids and anticoagulants such as aspirin Patients with a history of asthma and allergies Patients with uncontrolled systemic disorders Patients with a history of head and neck radiotherapy or chemotherapy Pregnant women and nursing mothers Patients who consume any amount of cigarettes, alcohol, drugs or stimulants

Design outcomes

Primary

MeasureTime frame
Pain score. Timepoint: Time intervals 1 hour, 6 hours, 12 hours, 24 hours, 48 ??hours and 72 hours after surgical treatment. Method of measurement: Questionnaire.;Dry socket occurrence. Timepoint: Fourth day after surgery. Method of measurement: Patient follow-up.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Mehmandust

Islamic Azad University

mostafa.a.sharifzadeh@gmail.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026