Condition 1: Chronic Kidney Disease (CKD), stages III. Condition 2: Chronic Periodontitis —Participants correspond to Stage II and Stage III periodontitis according to the 2017 World Workshop classification. Condition 3: Chronic Kidney Disease (CKD), stages IV. Chronic kidney disease, stage 3 (moderate) Chronic periodontitis Chronic kidney disease, stage 4 (severe)
Conditions
Interventions
Intervention 1: After recording baseline periodontal parameters, participants will receive non-surgical periodontal therapy (NSPT) including plaque removal, plaque control, supra- and subgingival scal
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: Chronic kidney disease stage 3 and 4 Periodontitis (stage I, II) Have at least 20 teeth
Exclusion criteria
Exclusion criteria: Smoking Pregnancy or lactation Patients with systemic disease affecting the periodontium (other than blood pressure) Patients who underwent periodontal treatment in the past 6 months Patients who have received antibiotics for one week in the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinine. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Modified Jaffe colorimetric method.;Estimated Glomerular Filtration Rate. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Calculated using CKD-EPI equation based on serum creatinine.;Blood Urea Nitrogen. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Enzymatic colorimetric method (Urease–GLDH). | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival Index. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Based on gingival observation.;Plaque Index. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Based on the use of probes and observations.;Bleeding on probing. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: It is evaluated as a percentage by probing in four areas: mesial, distal, buccal, and lingual.;Probing pocket depth. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Probe.;Clinical attachment loss. Timepoint: At the beginning of the study (before the intervention), 3 and 6 months after the intervention. Method of measurement: Measured in millimeters by Williams probe. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Reza Ahmadinia
Gorgan University of Medical Sciences
Outcome results
None listed