Infraorbital aging/ Infraorbital darkness/ Periorbital wrinkles. Other melanin hyperpigmentation
Conditions
Interventions
Intervention Group (Treatment):Participants in this group will receive a single injection of autologous biofiller (plasma gel) in the infraorbital area. The plasma gel will be prepared from the partic
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18 or older Mild to moderate infraorbital aging is defined as darkness or fine wrinkles not caused by systemic disease No active infection in periorbital area Informed consent of patient
Exclusion criteria
Exclusion criteria: Systemic disease affecting infraorbital area Coagulation disorder Combination therapy with other modalities ( , topical therapy, laser, RF, botox, hyaluronic acid filler ...) Active infection in periorbital area No informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infraorbital wrinkles. Timepoint: Before procedure and 3 months after procedure. Method of measurement: Objective assessments are performed using the Dermacatch imaging system. Subjective improvement is evaluated using the Patient Global Assessment (PGA), in which participants rated their overall satisfaction with the treatment outcome on a 4-point scale (1 = no improvement, 4 = excellent improvement). In addition, a Visual Analogue Scale (VAS) was used for subjective assessment, where both patients and the physician independently scored satisfaction with the treatment outcome on a 10-point scale (1 = not satisfied, 10 = fully satisfied). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYasamin Dehghan
Shiraz University of Medical Sciences
Outcome results
None listed