obstructive sleep apnea (OSA). Obstructive sleep apnea (adult) (pediatric)
Conditions
Interventions
Intervention 1: Intervention group: Calcitriol group 0.25 micrograms, four times a day, for 8 weeks
Tehran Daroo Co., Iran) during the intervention period. Drug packets in identical packaging will be delivered to participants by a trained person who is unaware of the drug and the patients. Patients
Sponsors
Vice President for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 65 years Vitamin D deficiency (<20 mg/dl) Patients with mild to moderate obstructive sleep apnea (OSA) who do not require continuous positive airway pressure (CPAP) No immune system deficiency No platelet deficiency No acute systemic diseases No mental and cognitive diseases that make communication with the patient impossible
Exclusion criteria
Exclusion criteria: Having chronic diseases that cause sleep disorders Unwillingness to cooperate Has taken vitamin-mineral supplements or fish oil in the past 6 months Impaired liver and kidney function Normal vitamin D levels Taking medications that affect vitamin D levels (such as steroids and anticonvulsants) Cancer Hypercalcemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep quality. Timepoint: before and 8 weeks after intervention. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Respiratory Quality. Timepoint: before and 8 weeks after intervention. Method of measurement: St. George's Respiratory Quality Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Laleh Mahmoudi
Shiraz University of Medical Sciences
Outcome results
None listed