Evaluation of the Effect of Low-Level Laser Therapy on Reducing Pain After Root Canal Treatment

Evaluation and Comparison of the Effects of Low-Level Laser Therapy at 810 nm and 660 nm in Reducing Postoperative Pain Following Root Canal Treatment of Maxillary and Mandibular Premolars and Molars with Irreversible Pulpitis Accompanied by Apical Periodontitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250923067345N1

Enrollment

Registered

2025-10-01

Start date

2025-09-27

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after root canal treatment in posterior teeth with irreversible pulpitis accompanied by symptomatic apical periodontitis in the maxilla and mandible..

Interventions

Intervention 1: Intervention Group 1: Laser irradiation at a wavelength of 660 nm with a power of 100 W and an energy of 4 J for 40 seconds over an area of 1 cm² at the apex of the treated tooth, appl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals with irreversible pulpitis accompanied by symptomatic apical periodontitis in mandibular and maxillary premolars and molars, eligible for single-visit root canal treatment. No use of analgesics within 48 hours prior to treatment. Based on the Heft-Parker (HPS) scale, patients with a pre-treatment VAS score above 54 are included in the study.

Exclusion criteria

Exclusion criteria: Patients with systemic diseases Pregnant or breastfeeding women Treatment of calcified teeth Patients seeking secondary or retreatment procedures Patients currently taking anti-inflammatory medications

Design outcomes

Primary

Measure	Time frame
Postoperative Pain. Timepoint: 4, 8, 12, and 24 hours after laser irradiation. Method of measurement: Pain intensity will be measured using the Heft-Parker Visual Analog Scale (VAS, HPS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnahita Alikhani

Islamic Azad University

Anahitaalkh@gmail.com+98 933 197 3330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026