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Investigating the effect of topical Tranexamic acid on edema and ecchymosis in 3 and 7 days after Rhinoplasty

Investigating the effect of topical Tranexamic acid on edema and ecchymosis in 3 and 7 days after Rhinoplasty

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250923067335N1
Enrollment
45
Registered
2025-09-24
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are definite candidates for rhinoplasty surgery. Encounter for cosmetic surgery

Interventions

Intervention 1: Intervention group: It includes the side of the nose that receives a local injection of tranexamic acid during rhinoplasty surgery, in addition to normal saline, epinephrine, and lidoc

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Having written informed consent to participate in the study Definite candidate for rhinoplasty surgery Age 18 to 60 years

Exclusion criteria

Exclusion criteria: Unwillingness to continue participating in the study History of coagulation disorder or thrombosis, revision surgery, or crooked nose

Design outcomes

Primary

MeasureTime frame
Edema around the eyes. Timepoint: Three and seven days after rhinoplasty surgery. Method of measurement: A standard 4-point scoring tool using an observational method. Zero means no edema, one means minimal edema, two means covering the iris, three means involving the pupil, and four means extensive edema in the upper and lower eyelids around the eye.;Ecchymosis around the eyes. Timepoint: Three and seven days after rhinoplasty surgery. Method of measurement: A standard 4-point scoring tool using an observational method. Zero means no ecchymosis, one means extension towards the inner canthus, two means extension towards the pupil, three means pupil involvement, and four means extension towards the outer canthus.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJahangir Ghorbani

Shahid Beheshti University of Medical Sciences

jjghorbani@gmail.com+98 21 2610 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026