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Zilomole in myopia

THE effect of timolo /dorzolamide eye drops on myopia progression in children

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250922067322N1
Enrollment
100
Registered
2025-12-21
Start date
2026-01-21
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

progression of myopia. Myopia, bilateral

Interventions

Intervention 1: Control group: Children with progressive myopia greater than -1.0 D, confirmed by clinical exam, will be followed without treatment. At baseline and at months 4, 8, and 12, full cyclop
Tono-Pen if uncooperative) will be measured and recorded. Intervention 2: Intervention group: Children with myopic refraction greater than -1.0 D, whose progressive myopia has been confirmed based on

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 17 Years

Inclusion criteria

Inclusion criteria: progrressive myopia more than -1

Exclusion criteria

Exclusion criteria: patient with strabismus, amblyopia or one eye

Design outcomes

Primary

MeasureTime frame
Refractive error. Timepoint: Before starting medication and then at months 4, 8, and 12. Method of measurement: Cycloplegic refraction with autorefractometer.

Secondary

MeasureTime frame
Changes in Axial length of the eye. Timepoint: Before starting the medication and also in the fourth, eighth and twelfth months. Method of measurement: with an optical biometry device.;Changes in intra ocular pressure. Timepoint: Before starting the medication and also in the fourth, eighth and twelfth months. Method of measurement: Tonopen device in uncooperative children and Goldmann tonometer for others.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Fatemeh Bakhshian

Shahid Beheshti University of Medical Sciences

Tara.bakhshian@gmail.com+98 21 2233 2948

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026