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Efficacy and safety of topical Rhenium-188 therapy in the treatment of skin cancer

Efficacy and safety of topical Rhenium-188 therapy and its comparison with cryotherapy in the treatment of basal cell carcinoma of the skin: a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250921067313N1
Enrollment
30
Registered
2025-10-05
Start date
2025-10-18
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Basal cell carcinoma of the skin. Other and unspecified malignant neoplasm of skin

Interventions

Intervention 1: Intervention group: The patients will be treated topically with rhenium-188. Radioactive rhenium-188 skin cream will be prepared from Pars Isotope Company and applied to the skin lesio

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Confirmed diagnosis of basal cell carcinoma in skin No involvement of lymph nodes or distant metastasis Patient preference or clinical condition for non-surgical intervention

Exclusion criteria

Exclusion criteria: Tumor thickness more than 3 millimeter Very close location of the tumor to vital and important organs such as the eyes

Design outcomes

Primary

MeasureTime frame
Reducing the size of the tumor. Timepoint: At baseline and at monthly intervals after the intervention (up to 3 months later). Method of measurement: By measuring the longest diameter of the tumoral lesion.

Secondary

MeasureTime frame
Complications of the treatment. Timepoint: At monthly intervals after the intervention (up to 3 months later). Method of measurement: Medical visit of the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNaser Emadi

Tehran University of Medical Sciences

naseremad@yahoo.com+98 21 5288 8282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026