The effect of herbal medicine on oral lichen planus study

Investigating the effect of herbal products (German chamomile or"Matricaria chamomilla" and Common marshmallow or" Althaea officinalis ") based on Persian medicine compared to oral gel triamcinolone in patients with oral lichen planus: A randomizedclinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250911067210N2

Enrollment

Registered

2025-09-30

Start date

2025-10-17

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral lichen planus. Lichen planus

Interventions

Intervention 1: Intervention group: Chamomile and marshmallow oral gel (5% aqueous extract of chamomile flowers and 5% of marshmallow aerial parts (flowers)) four times a day topically for two months.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosis of lichen planus by a dermatologist Patients with positive pathology Mild to moderate oral lesions

Exclusion criteria

Exclusion criteria: People with immunodeficiency Diabetes Pregnancy Osteomyelitis Peripheral vascular disease Use of systemic medications Severe degrees of oral lichen planus lesions

Design outcomes

Primary

Measure	Time frame
Change in lesion severity on examination based on REU score. Timepoint: Before the start of the intervention, and then after the intervention at specific time periods (0, 1, 2, and 3 months after the intervention) on a monthly basis. Method of measurement: Clinical exam.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Zarei

Tehran University of Medical Sciences

drzarei.azadeh@gmail.com+98 21 8897 6527

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026