Secondary Psychosis. Other stimulant related disorders
Conditions
Interventions
Intervention 1: The intervention group will receive electroconvulsive therapy (ECT) combined with standard antipsychotic pharmacotherapy. The ECT protocol consists of 6 sessions (3 sessions per week)
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of methamphetamine-induced psychosis Age 18-65 years Severe psychotic symptoms No response to initial pharmacotherapy (=72 hours) Written informed consent from patient or legal guardian No contraindications for Electroconvulsive Therapy
Exclusion criteria
Exclusion criteria: Presence of acute or unstable medical conditions. Any absolute medical contraindication to the study interventions. Coexisting psychiatric disorders that could confound clinical assessment. requirement for immediate specific intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total score of the Positive and Negative Syndrome Scale (PANSS). Timepoint: Before the intervention, week 2, week 4, and week 6 after the end of the intervention. Method of measurement: Assessment with Positive and Negative Syndrome Scale (PANSS) by trained psychiatrist in controlled setting. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactdr,Zeinab HeidariMokarrar
Zahedan University of Medical Sciences
Outcome results
None listed