Assessing the impact of two chosen exercise techniques on alterations in specific biomarkers and physiological indicators in children diagnosed with type 1 diabetes.

Assessing the impact of two selected exercise training on the alterations in the expression of miRNA-25, miRNA-93, and some physiological parameters in children diagnosed with type 1 diabetes.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20250908067184N1

Enrollment

Registered

2025-11-10

Start date

2025-12-06

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes. Diabetes mellitus due to underlying condition

Interventions

Intervention 1: The intervention group 1: Participants in this group will perform a selected aerobic exercises for 8 weeks. Intervention 2: Intervention Group 2: Participants in this group will partak

Eligibility

Sex/Gender

Female

Age

12 Years to 15 Years

Inclusion criteria

Inclusion criteria: An absence of participation in routine physical activities during the preceding year Type 1 diabetes identified by a medical expert Being within the age range of 12 to 15 years

Exclusion criteria

Exclusion criteria: Participants' free withdrawal from further interventions Physical injury during interventions Having other specific diseases Absence of more than 3 sessions in designated exercise interventions

Design outcomes

Primary

Measure	Time frame
Lipid Profile. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: Measurements are conducted utilizing specialized kits.;Insulin. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The assessment of insulin levels is conducted through the utilization of immunoassay-based insulin analysis kits.;Blood sugar. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: Blood glucose levels are assessed through the use of blood glucose kits and the photometric technique.;MiRNA-25. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The levels of miRNA-25 are extracted from blood serum using special kits and a real-time PCR device.;MiRNA-93. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The levels of miRNA-93 are extracted from blood serum using special kits and a real-time PCR device.;Cardiorespiratory endurance. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The participants' cardiorespiratory endurance will be determined using a 20-meter shuttle run test.	—

Measure

Time frame

Lipid Profile. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: Measurements are conducted utilizing specialized kits.;Insulin. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The assessment of insulin levels is conducted through the utilization of immunoassay-based insulin analysis kits.;Blood sugar. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: Blood glucose levels are assessed through the use of blood glucose kits and the photometric technique.;MiRNA-25. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The levels of miRNA-25 are extracted from blood serum using special kits and a real-time PCR device.;MiRNA-93. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The levels of miRNA-93 are extracted from blood serum using special kits and a real-time PCR device.;Cardiorespiratory endurance. Timepoint: Prior to the intervention and following 8 weeks of exercise interventions. Method of measurement: The participants' cardiorespiratory endurance will be determined using a 20-meter shuttle run test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiyayesh Gheisari

The University of Isfahan

niyayeshgheisari367@gmail.com+98 31 3232 0846

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026