Rectal Cancer.
Conditions
Interventions
Intervention 1: Intervention group: Open Upper Rectal Cancer Surgery Group. Intervention 2: Intervention group: Laparoscopic surgery group for upper rectal cancer. Intervention 3: Intervention group:
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 45 years old Upper and middle rectal cancer must be definitively diagnosed based on preoperative imaging results. Patients must be in stages 2 and 3 of upper and middle rectal cancer staging based on the TNM system. No history of surgery in the colon, rectum, or prostate area. No cancer metastasis to surrounding or distant organs (prostate, uterus, vagina, liver, lungs) Patients should not have urinary problems, such as stress incontinence and neuromuscular diseases that affect sphincter function. No history of lumbar disc surgery or any spinal cord injury that causes urinary, sexual, or bowel dysfunction. Not having inflammatory bowel diseases such as ulcerative colitis
Exclusion criteria
Exclusion criteria: Disease progression or recurrence: Patients who experience significant disease progression or recurrence during the waiting period until surgery. Non-compliance with the study protocol: Patients who fail to fully comply with the study protocol, including failure to complete questionnaires on time, failure to perform necessary tests, or failure to attend treatment sessions and follow-ups.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal function. Timepoint: One week before surgery and 1, 3, and 6 months after surgery. Method of measurement: Low Anterior Resection Syndrome (LARS) Questionnaire.;Urinary symptoms. Timepoint: One week before surgery and 1, 3, and 6 months after surgery. Method of measurement: International Prostate Symptom Score(IPSS) in Men, ICIQ-FLUTS in Women.;Sexual function. Timepoint: One week before surgery and 1, 3, and 6 months after surgery. Method of measurement: Female Sexual Function Questionnaire (FSFI) and International Index of Erectile Function (IIEF) in men.;Quality of life. Timepoint: One week before surgery and 1, 3, and 6 months after surgery. Method of measurement: Colorectal Cancer Quality of Life Questionnaire Appendix 29 QLQ-CR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: One day, two weeks, and one month after surgery. Method of measurement: Visual analog scale.;Bleeding. Timepoint: One day, two weeks, and one month after surgery. Method of measurement: The amount of blood collected in the suction bottle and the method of accurately weighing gases during the operation and measuring the discharge from the drainage tubes after the operation.;Surgery Time. Timepoint: During surgery. Method of measurement: Stopwatch and in minutes.;Fecal incontinence. Timepoint: One month, three months, and six months after the operation. Method of measurement: Wexner Fecal Incontinence Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRohollah Taghavi
Hamedan University of Medical Sciences
Outcome results
None listed