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Study of the effect of ligature and harmonic in laparoscopic colorectal cancer surgery

Comparative Evaluation of the Performance of Ligasure and Harmonic Scalpel in Laparoscopic Colorectal Cancer Surgeries: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250908067174N2
Enrollment
60
Registered
2025-09-28
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Colon Cancer. Condition 2: Rectum cancer. Malignant neoplasm of colon Malignant neoplasm of rectum

Interventions

Intervention 1: Intervention group1: After performing a laparoscopic port placement, we use a ligature device to release the omentum from the colon or rectum or to tie off the vessels and arteries. Af

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Willingness to participate in the research process and signing a written and informed consent form Eligibility for laparoscopic surgery and clinical documentation confirming colorectal cancer Being over 18 years old Having minimum literacy to complete the questionnaire form Possibility of following up on the patients' condition for up to one month after the operation

Exclusion criteria

Exclusion criteria: Unwillingness to continue the intervention Previous major abdominal surgeries Conversion of laparoscopic surgery to laparotomy surgery Heart diseases including uncontrolled blood pressure - Ejection fraction (less than 50%) patients with coagulation problems (according to PT - PTT) Patients who have taken aspirin or anticoagulants 5 days before surgery Uncontrolled diabetes

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: Pain measurement 6-12-18-24-48 hours after surgery. Method of measurement: Pain measurement will be performed using a visual analog scale after surgery.;Intraoperative bleeding. Timepoint: During surgery. Method of measurement: The amount of bleeding during surgery will be measured based on the amount of bleeding inside the suction bottle and blood gases. In this way, the blood in the suction bottle is measured with a 50 cc syringe and the gases are weighed before and after surgery and the amount of bleeding is obtained.;Postoperative bleeding. Timepoint: Up to a week after surgery. Method of measurement: The amount of bleeding after surgery will be measured according to the drains installed for the patients. In this way, the amount of bleeding and secretions will be measured with a gavage syringe.;Pre- and postoperative hemoglobin levels. Timepoint: one day before and one day after surgery. Method of measurement: Complete blood count test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRohollah Taghavi

Hamedan University of Medical Sciences

fateme1380samiee@gmail.com+98 25 3212 2200

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026