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The effect of quetiapine on cannabis users

The effect of quetiapine on craving and cognitive performance of cannabis users

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20250906067145N1
Enrollment
70
Registered
2025-09-23
Start date
2025-10-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction. Other psychoactive substance related disorders

Interventions

Intervention 1: Intervention group: Quetiapine tablets at a dose of 100 mg manufactured by Tadbir Kala Jam Pharmaceutical Company, 1 tablet daily, were used for 8 weeks of intervention. Intervention 2

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 30 Years

Inclusion criteria

Inclusion criteria: Age 15 to 30 years Meeting the criteria for cannabis dependence according to DSM-V-TR along with the client's self-report of ongoing cannabis use

Exclusion criteria

Exclusion criteria: Illiterate people Cognitive impairment (congenital or acquired) Symptoms of psychosis Suicidal thoughts Cocaine addiction Alcohol dependence Cardiovascular disorders Recent use of over-the-counter or prescription medications that are expected to have a major interaction with Quetiapine Metabolic diseases (such as epilepsy, diabetes, and neurological diseases) Dissatisfaction Patients who are unable to perform tests due to lack of concentration

Design outcomes

Primary

MeasureTime frame
Cannabis craving. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: DDQ questionnaire.;Cognitive performance of cannabis users. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Addenbrooke's Cognitive Inventory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMotahhare Mansoornejhad

Kashan University of Medical Sciences

mansoorneghad-m@kaums.ac.ir+98 31 3457 4191

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026