Anxiety in patients undergoing colonoscopy under anesthesia. Generalized anxiety disorder
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: Patients in this group will receive 3 milligrams of oral melatonin (manufactured by Actoverco Pharmaceutical Company) in the form of a tablet 50
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 55 Years
Inclusion criteria
Inclusion criteria: ASA class I or II Age between 15 to 55 years Non-emergency colonoscopy BMI between 19 to 25 No use of narcotics in the past week No history of thyroid, neuromuscular, kidney, or psychiatric diseases Informed consent for participation Equal number of male and female participants Duration of colonoscopy between 10 to 45 minutes Not enrolled in any other clinical trial
Exclusion criteria
Exclusion criteria: Patients who wish to withdraw from the study Underlying conditions making sedation unsafe Use of benzodiazepines in the past 72 hours Prolonged colonoscopy duration Complications during colonoscopy Need for ileoscopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of anxiety before anesthesia in patients undergoing colonoscopy. Timepoint: 50 minutes before anesthesia induction. Method of measurement: Visual Analogue Scale Score for anxiety, recorded by trained staff. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of nausea and vomiting in patients undergoing colonoscopy under general anesthesia, assessed as a secondary outcome of oral melatonin administration. Timepoint: Before anesthesia, during colonoscopy (every 10 minutes), and after colonoscopy in the recovery room (every 15 minutes) until patient reaches an Aldrete score of 8. Method of measurement: Nausea and vomiting will be recorded based on direct clinical observation and patient self-reporting, documented in a standardized patient evaluation form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Sobhani
Mazandaran University of Medical Sciences
Outcome results
None listed